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Updated: May 8, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
Published on: October 25, 2015
Fetal anesthesia and pain management for intrauterine therapy
Roland Brusseau1, Arielle Mizrahi-Arnaud
1Department of Anesthesia, Perioperative and Pain Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. roland.brusseau@childrens.harvard.edu
Abstract:
Anesthesia provision for fetal intervention differs from most other anesthetic situations insofar as anesthesiologists must care for 2 or more patients-each with potentially conflicting requirements. The first is the mother who can readily indicate discomforts, can be monitored directly, and to whom drugs may be administered directly and easily. For the fetus (or fetuses), nociception must be assumed or inferred indirectly, monitoring is limited at best, and drug administration is complicated and often indirect. Fetal and maternal hemodynamic stability must be assured; and a plan to resuscitate the fetus, should problems occur during the procedure, must be developed.
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