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Updated: May 8, 2026

A Neonatal Rodent Model of Retroorbital Vein Injection
Published on: February 23, 2024
Regional anesthesia in neonates and infants
Adrian Bosenberg1, Randall P Flick
1Department of Anesthesiology and Pain Management, Faculty Health Sciences, Seattle Children's Hospital, University Washington, 4800 Sandpoint Way Northeast, Seattle, WA 98105, USA.
Optimal pain management can significantly impact the surgical outcome and length of stay in the neonatal intensive care unit (NICU). Regional anesthesia is an effective alternative that can be used in both term and preterm neonates. A variety of neuraxial and peripheral nerve blocks have been used for specific surgical and NICU procedures. Ultrasound guidance has increased the feasibility of using these techniques in neonates. Education and training staff in the use of continuous epidural infusions are important prerequisites for successful implementation of regional anesthesia in NICU management protocols.
Optimal pain management can significantly impact the surgical outcome and length of stay in the neonatal intensive care unit (NICU). Regional anesthesia is an effective alternative that can be used in both term and preterm neonates. A variety of neuraxial and peripheral nerve blocks have been used for specific surgical and NICU procedures. Ultrasound guidance has increased the feasibility of using these techniques in neonates. Education and training staff in the use of continuous epidural infusions are important prerequisites for successful implementation of regional anesthesia in NICU management protocols.
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