Related Experiment Video

Updated: May 8, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

Epidemiology of Group B Streptococcus in developing countries

Atul Kumar Johri1, Hem Lata, Puja Yadav

  • 1School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India. akjohri14@yahoo.com

Vaccine
|August 27, 2013
PubMed

Insights

Group B Streptococcus (GBS) causes serious neonatal infections. Understanding GBS serotype distribution in India, China, and Brazil is crucial for developing effective vaccines and public health interventions.

Area of Science:

  • Microbiology
  • Epidemiology
  • Public Health

Background:

  • Group B Streptococcus (GBS) is a significant cause of neonatal pneumonia, meningitis, and sepsis.
  • The current distribution of GBS serotypes in developing nations like India, China, and Brazil remains unclear.
  • Accurate serotype data is essential for targeted vaccination strategies.

Purpose of the Study:

  • To highlight the urgent need for prospective, population-based studies on GBS serotype distribution in developing countries.
  • To inform the planning of vaccination programs aimed at reducing GBS disease burden.
  • To present available data and identify research gaps in India, China, Brazil, and other developing nations.

Main Methods:

  • Review of existing data and literature on GBS serotype prevalence.
  • Discussion among workgroup members focusing on India, China, and Brazil.
  • Identification of knowledge gaps and recommendations for future research.

Main Results:

  • The current distribution of GBS serotypes in India, China, and Brazil is not well-defined.
  • Prospective population-based studies are urgently required to establish accurate distribution patterns.
  • Data from other developing countries were also considered.

Conclusions:

  • Further research, particularly prospective population-based studies, is essential in developing countries.
  • Understanding GBS serotype epidemiology is critical for effective public health interventions and vaccine development.
  • Targeted studies in India, China, and Brazil will aid in disease burden reduction.

Keywords:
Group B StreptococcusMaternal immunizationNeonatal

More Related Videos

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/4306:06

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43

Published on: September 11, 2020

Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...