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Updated: May 8, 2026

The Quantification of Injectability by Mechanical Testing
Published on: May 13, 2020
Quality-Control Analytical Methods: Particulate Matter In Injections: What is It and What are the Concerns?
Tuan Tran1, Thomas K Kupiec, Lawrence A Trissel
1University of Oklahoma Health Sciences Center, College of Pharmacy, Oklahoma City, Oklahoma.
Abstract:
The presence of particulate matter in intravenous injections, especially in large numbers, represents a potentially life-threatening health hazard. The United States Pharmacopeia has established procedures and standards to ensure the quallity of intravenous injections, including particulate counts. Compounding pharmacists can reduce the incidence of adverse events in patients by assuring the quality of their preparations through filtration of intravenous preparations and analytical testing procedures.
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