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Well and intermediate differentiated laryngeal chondrosarcoma: toward conservative surgery?
Valerio Damiani1, Erika Crosetti, Giuseppe Rizzotto
1ENT Department, San Giovanni-Addolorata Hospital, Rome, Italy, valerio_damiani@me.com.
Summary
Conservative surgery for laryngeal chondrosarcoma (LCS) effectively preserves voice and swallowing. This approach, utilizing endoscopic or open techniques, shows no recurrence in a 31-month follow-up for six patients.
Area of Science:
- Otolaryngology
- Surgical Oncology
- Pathology
Background:
- Laryngeal chondrosarcoma (LCS) is a rare non-epithelial tumor, typically affecting the cricoid cartilage.
- Fewer than 600 cases of LCS have been documented globally.
Purpose of the Study:
- To evaluate the efficacy of conservative surgical approaches for laryngeal chondrosarcoma.
- To assess functional outcomes and recurrence rates following organ-sparing surgery for LCS.
Main Methods:
- Retrospective analysis of six cases of well-intermediate differentiated chondrosarcoma of the larynx.
- Surgical interventions included endoscopic transoral laser surgery and open supratracheal partial laryngectomy (STL).
- Patient selection criteria were based on age, cricoid involvement, and cricoarytenoid joint status.
Main Results:
- All six patients achieved recurrence-free survival with a minimum follow-up of 31 months.
- Patients regained satisfactory speech and swallowing function, with decannulation achieved in all cases.
- Conservative surgery successfully spared laryngeal function, avoiding total laryngectomy.
Conclusions:
- Conservative surgical management, including endoscopic and STL techniques, is effective for laryngeal chondrosarcoma.
- Organ-sparing surgery for LCS can yield excellent functional outcomes and long-term disease control.
- Supratracheal partial laryngectomy expands surgical indications for LCS, preserving laryngeal function.
