Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

Issues And Trends In Healthcare Delivery System

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

Pharmacogenomics: Identification of New Drug Targets

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

Next-generation Sequencing

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

Modern Molecular Taxonomy

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

*informatics: Identifying and Tracking Informatics Sub-Discipline Terms in the Literature.

Methods of information in medicine·2015

Same author

Managing interoperability and complexity in health systems.

Methods of information in medicine·2015

Same author

Evaluation of biomedical informatics innovations and their impact on public health.

Methods of information in medicine·2012

Same author

The birth and evolution of a discipline devoted to information in biomedicine and health care. As reflected in its longest running journal.

Methods of information in medicine·2011

Same author

Biomedical informatics--a confluence of disciplines?

Methods of information in medicine·2011

Same author

Data analysis and data mining: current issues in biomedical informatics.

Methods of information in medicine·2011

Same journal

Citizens' Options When Accessing and Sharing Health Information - An International Survey of IMIA Member Countries.

Yearbook of medical informatics·2025

Same journal

Social Determinants of Health in Digital Health Policies: an International Environmental Scan.

Yearbook of medical informatics·2025

Same journal

Sensors, Signals, and Imaging Informatics: Best contributions from 2023.

Yearbook of medical informatics·2025

Same journal

Alzheimer Disease Detection Studies: Perspective on Multi-Modal Data.

Yearbook of medical informatics·2025

Same journal

Exploring the Latest Advances in Public Health and Epidemiology Informatics.

Yearbook of medical informatics·2025

Same journal

Application of Digital Informatics in Precision Prevention, Epidemiology, and Clinicogenomics Research to Advance Precision Healthcare.

Yearbook of medical informatics·2025

See all related articles

Search research articles

Related Experiment Video

Updated: May 8, 2026

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

Bringing genome tests into clinical practice.

¹Center for Clinical and Translational Science, University of Vermont, 89 Beaumont Avenue, Given Courtyard N309, Burlington, VT 05405 USA.

Yearbook of Medical Informatics

|August 27, 2013

Summary

This summary is machine-generated.

Genomic data integration into electronic health records is advancing for clinical decision-making. Research also focuses on the clinical utility of genomic tests for future healthcare applications.

More Related Videos

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

Related Experiment Videos

Last Updated: May 8, 2026

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

Area of Science:

Genomics in Medicine
Clinical Bioinformatics

Background:

The increasing volume of genomic data presents challenges and opportunities for clinical practice.
Translating genomic discoveries into actionable clinical insights is a key goal in modern healthcare.

Purpose of the Study:

To review recent advancements in applying genomic data within clinical settings.
To identify key trends in genomic data utilization from the past year (2012).

Main Methods:

A targeted literature review of scientific articles published in 2012.
Analysis focused on studies related to genomic data integration and clinical utility.

Main Results:

Two primary themes dominated 2012: integrating genomic data into electronic health records (EHRs) and assessing the clinical utility of genomic tests.
Progress was noted in developing systems for seamless genomic data incorporation into EHRs.

Conclusions:

Substantial progress is being made to integrate genomic data for improved clinical decision-making.
While genotype-phenotype research remains crucial, promising developments in clinically useful genomic tests are emerging for the near future.