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Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
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Published on: March 25, 2016

Anagen effluvium.

Amrinder J Kanwar1, Tarun Narang

  • 1Department of Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Indian Journal of Dermatology, Venereology and Leprology
|August 27, 2013
PubMed
Summary
This summary is machine-generated.

Anagen effluvium, or abrupt hair loss during the growing phase, is often linked to chemotherapy but has other causes. Management requires addressing the hair loss and its psychological impact.

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Area of Science:

  • Dermatology
  • Trichology
  • Hair Biology

Background:

  • Hair follicle cycling disturbances cause common hair growth disorders.
  • Anagen effluvium, characterized by hair loss during the anagen (growing) phase, is often conflated with chemotherapy-induced alopecia.
  • Limited literature reviews focus on anagen effluvium beyond chemotherapy-induced causes.

Purpose of the Study:

  • To review the etiopathogenesis, clinical presentation, differential diagnoses, and management of anagen effluvium.
  • To broaden the understanding of anagen effluvium beyond chemotherapy-induced alopecia.
  • To highlight the psychological impact and management strategies for anagen effluvium.

Main Methods:

  • Literature review focusing on anagen effluvium.
  • Analysis of causes including chemotherapy, radiation, toxic chemicals, and inflammatory conditions.
  • Discussion of clinical presentation, differentials, and management approaches.

Main Results:

  • Anagen effluvium results from impaired hair follicle mitotic or metabolic activity during the anagen phase.
  • Causes include chemotherapy, radiation, toxins, and inflammatory diseases like alopecia areata.
  • Hair regrowth typically occurs within 1-3 months, but permanent alopecia is possible.

Conclusions:

  • Anagen effluvium is a significant hair loss disorder with diverse etiologies.
  • Management should encompass medical treatment, psychological support, and practical aesthetic advice.
  • Addressing the psychological distress associated with anagen hair loss is crucial for patient well-being and treatment adherence.