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Related Concept Videos

Accessory Structures of the Skin: Hair Growth and Types01:20

Accessory Structures of the Skin: Hair Growth and Types

Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
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Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
Accessory Structures of the Skin: Hair and Hair Follicles01:16

Accessory Structures of the Skin: Hair and Hair Follicles

Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
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Folliculogenesis01:20

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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

Female pattern hair loss.

Archana Singal1, Sidharth Sonthalia, Prashant Verma

  • 1Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, University of Delhi, Delhi, India.

Indian Journal of Dermatology, Venereology and Leprology
|August 27, 2013
PubMed
Summary
This summary is machine-generated.

Female pattern hair loss (FPHL) is common in women, often linked to genetics and aging. Early medical treatment, like minoxidil, is key to managing FPHL progression.

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Area of Science:

  • Dermatology
  • Endocrinology
  • Genetics

Background:

  • Female pattern hair loss (FPHL) is a prevalent condition affecting women, characterized by reduced hair density on the scalp.
  • Its prevalence increases with age and is associated with psychological distress.
  • The exact causes of FPHL are multifactorial, involving both androgen-dependent and independent mechanisms, as well as genetic factors.

Purpose of the Study:

  • To review the pathophysiology, diagnosis, and management of female pattern hair loss.
  • To highlight the role of genetic polymorphisms and androgen/estrogen receptors in FPHL.
  • To discuss current and potential treatment strategies for FPHL.

Main Methods:

  • Literature review of studies on female pattern hair loss.
  • Analysis of diagnostic criteria and differential diagnoses, including chronic telogen effluvium.
  • Evaluation of treatment modalities, including medical (minoxidil, anti-androgens) and surgical options.

Main Results:

  • FPHL pathophysiology is complex and not fully understood, with genetic factors playing a significant role.
  • Early medical intervention is crucial for arresting hair loss progression.
  • Minoxidil remains a first-line therapy, with anti-androgens as a second-line option.

Conclusions:

  • Accurate diagnosis through thorough evaluation is essential for effective patient management.
  • Long-term treatment is necessary for sustained results in FPHL.
  • Management may involve medical therapy, cosmetic solutions, and potentially surgery in select cases.