Underweight, overweight and obesity in paediatric dialysis and renal transplant patients

Marjolein Bonthuis1, Karlijn J van Stralen, Enrico Verrina

  • 1ESPN/ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Insights

Overweight and obesity are common in European children on renal replacement therapy (RRT), challenging the focus on malnutrition. Nutritional strategies must address both underweight and overweight/obesity in pediatric RRT patients.

Area of Science:

  • Pediatric Nephrology
  • Public Health
  • Nutritional Science

Background:

  • Childhood overweight is a global concern, yet poor nutrition remains primary in pediatric renal replacement therapy (RRT).
  • This study investigates the prevalence and factors of underweight and overweight/obesity in European children undergoing RRT.
  • It also examines body mass index (BMI) changes post-RRT initiation.

Purpose of the Study:

  • To determine the prevalence of underweight, overweight, and obesity in European children on RRT.
  • To identify factors associated with underweight and overweight/obesity in this population.
  • To analyze the changes in BMI after starting RRT.

Main Methods:

  • Analysis of BMI data from 4474 European pediatric RRT patients (1995-2010).
  • Utilized World Health Organization (WHO) and International Obesity Task Force (IOTF) criteria for BMI classification.
  • Data sourced from the European Society for Paediatric Nephrology/European Renal Association-European Dialysis and Transplant Association Registry.

Main Results:

  • Underweight prevalence was 3.5%; overweight was 20.8%; obesity was 12.5%.
  • Dialysis treatment and infant age were linked to underweight.
  • Short stature and glucocorticoid use were associated with overweight/obesity in transplant recipients.

Conclusions:

  • Overweight and obesity are more prevalent than underweight in European pediatric RRT patients.
  • Short stature is strongly linked to overweight in graft recipients; underweight is primarily an infant issue.
  • Nutritional management for pediatric RRT should equally address overweight/obesity prevention and treatment alongside malnutrition.
Abstract

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...