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Fibroblast growth factor receptor-2 expression in thyroid tumor progression: potential diagnostic application

Adriano Redler1, Giorgio Di Rocco, Domenico Giannotti

  • 1Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy.

Plos One
|August 27, 2013
PubMed
Summary

Fibroblast growth factor receptor-2 (FGFR-2) expression is reduced in thyroid adenoma and papillary carcinoma. This down-modulation may signal early thyroid cancer development, suggesting FGFR-2 as a potential diagnostic marker.

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