International E-vita open registry.

Area of Science:

• Cardiovascular Surgery
• Medical Device Technology
• Clinical Registry Studies

Background:

• Complex pathologies of the ascending aorta, aortic arch, and descending aorta require advanced treatment strategies.
• The E-vita open hybrid stent-graft is designed for one-stage repair of these challenging aortic conditions.

Purpose of the Study:

• To evaluate the efficacy and long-term durability of the E-vita open hybrid stent-graft.
• To assess outcomes in patients with acute dissection, chronic dissection, and multisegmental thoracic aneurysmal disease.

Main Methods:

• Initiation of the International E-vita open registry (IEOR) in 2008.
• Recruitment of 416 patients across 10 European centers.
• Categorization of patients into acute dissection, chronic dissection, and multisegmental aneurysmal disease groups.

Main Results:

• In-hospital mortality rates were 16% (acute dissection), 14% (chronic dissection), and 13% (aneurysmal disease).
• Stroke and spinal cord injury rates varied between 5-7% and 3-9% respectively.
• Five-year survival rates were 79%, 86%, and 78%, with freedom from reoperation at 96%, 94%, and 82% for the respective groups.

Conclusions:

• The E-vita open hybrid stent-graft facilitates successful one-stage repair for complex aortic pathologies.
• The IEOR registry provides crucial data for developing management guidelines and frameworks for thoracic aortic disease.