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Updated: May 8, 2026

Human Internal Mammary Artery (IMA) Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis
Published on: May 9, 2012
Bilateral internal mammary arteries: evidence and technical considerations
Michael P Vallely1, J James B Edelman, Michael K Wilson
1Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Sydney, Australia; ; The Baird Institute, Sydney, Australia; ; Sydney Medical School, The University of Sydney, Sydney, Australia; ; Australian School of Advanced Medicine, Macquarie University, Sydney, Australia.
Bilateral internal mammary artery (BIMA) grafts improve survival in coronary revascularization compared to single grafts. This review explores BIMA evidence and reasons for limited surgeon adoption.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Coronary artery bypass grafting (CABG) is a common procedure for coronary revascularization.
- Internal mammary artery (IMA) grafts are associated with superior long-term patency rates compared to saphenous vein grafts.
- Bilateral internal mammary artery (BIMA) grafting offers potential survival benefits over single IMA or vein grafts, yet its adoption is limited.
Purpose of the Study:
- To review the evidence supporting the use of BIMA grafts for coronary revascularization.
- To explore the reasons behind the suboptimal utilization of BIMA grafts by surgeons.
- To discuss technical aspects, graft strategies, and the role of BIMA in anaortic off-pump coronary artery bypass (OPCAB).
Main Methods:
- Literature review of studies comparing BIMA grafts with single IMA or vein grafts.
- Analysis of factors influencing surgeon choice regarding graft selection.
- Discussion of surgical techniques and graft configurations for BIMA utilization.
Main Results:
- Evidence suggests improved survival rates with BIMA grafting compared to single IMA or vein grafts.
- Several factors contribute to the limited use of BIMA, including perceived technical complexity and concerns about sternal wound complications.
- BIMA grafts can be effectively used in various combinations and facilitate OPCAB procedures.
Conclusions:
- BIMA grafting represents a valuable option for coronary revascularization, offering superior long-term outcomes.
- Addressing surgeon concerns through education and standardized techniques may increase BIMA adoption.
- Further research and surgeon education are crucial to optimize the use of BIMA for improved patient survival.
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