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Double fertilization in vitro and the origin of human chimerism
S J Van de Leur1, G H Zeilmaker
1Department of Endocrinology, Growth, and Reproduction, Erasmus University Rotterdam, The Netherlands.
Fertility and Sterility
|September 1, 1990
Abstract:
A human embryo consisting of two cells, each containing two pronuclei, was found in the IVF laboratory. The most likely explanation for this phenomenon is a parthenogenetic activation of an oocyte leading to immediate cleavage and followed by double fertilization. Human chimerism may originate in this way.