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Hypertension in women
1Division of Nephrology and Hypertension, Weill Cornell Medical College, New York, NY, USA. paugust@med.cornell.edu
Insights
Hypertension affects 1 billion adults globally. While men have higher blood pressure, women experience uncontrolled hypertension more often, yet treatment approaches remain similar for both genders.
Area of Science:
- Cardiology
- Public Health
- Endocrinology
Background:
- Hypertension impacts 1 in 4 adults globally, representing 1 billion individuals.
- It is a primary cause of mortality and morbidity.
- While men generally have higher blood pressure, older women exhibit a higher prevalence and less controlled hypertension.
Purpose of the Study:
- To review the global prevalence and characteristics of hypertension in adults.
- To highlight gender-specific aspects of hypertension, including unique conditions in women.
- To evaluate current hypertension management strategies regarding gender differences.
Main Methods:
- Systematic review of global hypertension prevalence data.
- Analysis of epidemiological studies on hypertension in men and women.
- Examination of literature on gender-specific hypertension etiologies and treatment outcomes.
Main Results:
- Hypertension affects approximately 1 billion adults worldwide.
- Older women show a higher prevalence and less controlled hypertension compared to men.
- Specific conditions like pregnancy-related hypertension, polycystic ovary syndrome, and fibromuscular dysplasia are more prevalent in women.
Conclusions:
- Hypertension management should prioritize blood pressure reduction and cardiovascular risk factor treatment.
- Current evidence does not support gender-specific strategies for blood pressure lowering or cardiovascular risk modification.
- Further research may be needed to explore potential nuances in hypertension management between genders.
Abstract:
One in 4 adults has hypertension worldwide, which equates to approximately 1 billion individuals. Hypertension is a leading cause of death, and lowering blood pressure prevents mortality and morbidity in women and men. Although men have higher blood pressures compared with women at all ages, older women have a slightly higher prevalence of hypertension, and hypertension is more often uncontrolled in women. Hypertension associated with pregnancy and polycystic ovary syndrome is unique to women. Exogenous hormone administration in the form of oral contraceptives, and rarely postmenopausal hormone replacement, contributes to the burden of hypertension in women. Renovascular hypertension due to fibromuscular dysplasia is more common in women. Hypertension treatment should focus on lowering blood pressure and treating additional cardiovascular risk factors, and there is no evidence to support gender-specific approaches to lowering blood pressure and modifying cardiovascular risk.
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