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Updated: May 8, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
09:32

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Published on: December 9, 2021

Operative and nonoperative management of chronic disseminated intravascular coagulation due to persistent aortic

Jeffrey J Nienaber1, Audra A Duncan1, Gustavo S Oderich1

  • 1Division of Vascular Surgery, Mayo Clinic, Rochester, Minn.

Journal of Vascular Surgery
|August 28, 2013
PubMed

Insights

Disseminated intravascular coagulation (DIC) from endoleaks after endovascular aneurysm repair is rare. Chronic thrombocytopenia, similar to cirrhosis, may be a risk factor for developing DIC due to endoleaks.

Area of Science:

  • Vascular Surgery
  • Hematology

Background:

  • Endovascular aneurysm repair (EVAR) is a common treatment for abdominal aortic aneurysms.
  • Endoleaks are a known complication of EVAR, potentially leading to serious adverse events.
  • Disseminated intravascular coagulation (DIC) is a rare but life-threatening complication associated with endoleaks.

Observation:

  • This study reports three cases of DIC secondary to delayed high-flow endoleaks (Type Ia or III) in patients who underwent EVAR.
  • Unlike previously reported cases, these patients had normal liver function.
  • All patients presented with chronic thrombocytopenia prior to the development of endoleaks.

Findings:

  • The three patients developed DIC due to delayed, high-flow endoleaks.
  • Two patients required surgical repair, while one was managed medically.
  • Chronic thrombocytopenia was a common feature in these patients and in previously reported cases.

Implications:

  • Chronic thrombocytopenia should be recognized as a potential risk factor for developing DIC following EVAR.
  • This finding may influence patient selection and perioperative management for EVAR.
  • Further research is warranted to elucidate the mechanisms linking thrombocytopenia and DIC in the context of endoleaks.

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