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Visualized changes in respiratory resistance and reactance along a time axis in smokers: a cross-sectional study

Haruko Shinke1, Masatsugu Yamamoto, Nobuko Hazeki

  • 1Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, Japan.

Respiratory Investigation
|August 28, 2013
PubMed
Summary

Early respiratory impedance changes, including elevated resistance and altered reactance, are detectable in approximately 60% of smokers with normal lung function, suggesting potential early airway remodeling.

Keywords:
3-dimensional3DCOPDChronic obstructive pulmonary diseaseFEV(1)FOTForced oscillation techniqueFresICSLABALAMAPFTR20R5R5subR5–R20 subRespiratory impedanceRrsRrs at 20HzRrs at 5HzSmall airway diseaseSmokerX5X5subXrsXrs at 5HzZrschronic obstructive pulmonary diseasedifference of R5 between maximum and minimum valuedifference of X5 between maximum and minimum valueforced expiratory volume in 1sforced oscillation techniquefrequency of resonanceinhaled corticosteroidsinhaled long-acting muscarinic antagonistlong-acting beta-agonistpulmonary function testrespiratory impedancerespiratory reactancerespiratory resistance

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