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Eosinophilic pleural effusions.

M S Lau1, F D Pien

  • 1University of Hawaii, John A. Burns School of Medicine.

Hawaii Medical Journal
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

This study reports two cases of eosinophilic pleural effusion (EPE), a condition defined by over 10% eosinophils in pleural fluid. Causes include infections and malignancies, though idiopathic cases are also common.

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Area of Science:

  • Pulmonology
  • Hematology
  • Pathology

Background:

  • Eosinophilic pleural effusion (EPE) is characterized by eosinophils comprising over 10% of the white blood cell differential in pleural fluid.
  • EPE typically presents as an exudative effusion, accounting for a small percentage of all pleural effusions.

Observation:

  • Two distinct cases of EPE were observed at Straub Hospital.
  • One case was associated with pneumococcal empyema, while the second involved recurrent EPE secondary to malignant histiocytic lymphoma.

Findings:

  • Common etiologies for EPE include air in the pleural space, pulmonary infections, collagen vascular diseases, tuberculosis, and malignancies.
  • Idiopathic EPE accounts for a significant proportion, estimated between 30% and 35% of cases.

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Implications:

  • While EPE often resolves spontaneously with a favorable prognosis, careful clinical follow-up is recommended.
  • Understanding the diverse causes of EPE is crucial for accurate diagnosis and management.