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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential

Samuel D Banister1, Miral Manoli, Melissa L Barron

  • 1School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.

Bioorganic & Medicinal Chemistry
|August 29, 2013
PubMed

Keywords:
1,3-di-o-tolylguanidine4-phenyl-1-(4-phenylbutyl)piperidine5-HT5-hydroxytryptamineCNSDADATDTGHEKHemiaminalIP(3)LPSMAMN-methyl-d-aspartateNENETNMDANONOSNeuroprotectionNitric oxidePCCPETPPBPROSSAfiRSERTSPECTSigma receptorTrishomocubaneVGCCscentral nervous systemdopaminedopamine transporterhuman embryonic kidneyinositol-1,4,5-triphosphatelipopolysccharidemitochondria-associated endoplasmic reticulum membranenitric oxidenitric oxide synthasenorepinephrinenorepinephrine transporterpositron emission tomographypyridinium chlorochromatereactive oxygen speciesserotonin transportersingle photon emission computerised tomographystructure–affinity relationshipvoltage-gated calcium channels

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