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Neuroimaging findings in Alexander's disease
G B Bobele1, A Garnica, G B Schaefer
1Department of Neurology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City 73126.
Journal of Child Neurology
|July 1, 1990
Abstract:
We present the findings from magnetic resonance imaging, computed tomographic scan, and single photon emission computed tomography of the brain in a 2-year-old girl with Alexander's disease. Computed tomographic scans showed prominent low-density white matter throughout the cerebral hemispheres. Magnetic resonance imaging showed increased T2 signal from the cerebral white matter but not the cerebellum or brain stem. Single photon emission computed tomography revealed diminished cerebral metabolism, particularly in the frontal regions, as compared with the cerebellum.