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Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization
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Peptide amphiphile nanoparticles enhance the immune response against a CpG-adjuvanted influenza antigen
Harshal Zope1, Christophe Barnier Quer, Paul H H Bomans
1Department of Soft Matter Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.
Abstract:
Cationic peptide amphiphile nanoparticles are employed for co-delivery of immune modulator CpG and antigen. This results in better targeting to the antigen presenting cells and eliciting strong Th1 response, which is effective against the intracellular pathogens.
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