Related Experiment Video
Updated: May 8, 2026

04:08
Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Placental Tumour: What could it be?
Nihal Al-Riyami1, Rahma Al-Hadabi, Tamima Al-Dughaishi
1Departments of Obstetrics & Gynaecology, Sultan Qaboos University Hospital, Muscat, Oman.
Sultan Qaboos University Medical Journal
|August 29, 2013
Summary
Large placental chorioangiomas, rare benign vascular tumors, can cause serious pregnancy complications. This case highlights antenatal management strategies and discusses maternal and fetal outcomes for these challenging cases.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Pathology
Background:
- Placental tumors encompass various types, including chorioangiomas, teratomas, hemangiomas, and hematomas.
- Placental chorioangiomas are the most common placental tumors, representing 1% of all placental tumors, and are benign vascular neoplasms.
- While typically small, large placental chorioangiomas are infrequent and associated with significant pregnancy complications and adverse perinatal outcomes.
Purpose of the Study:
- To present a case study of a large placental chorioangioma.
- To detail the antenatal management strategies employed for this rare condition.
- To evaluate the maternal and fetal outcomes in a case of large placental chorioangioma.
Main Methods:
- Case report detailing a large placental chorioangioma.
- Review of antenatal diagnostic and management protocols.
- Analysis of maternal and fetal outcomes post-delivery.
Main Results:
- The case involved a large placental chorioangioma presenting significant clinical challenges.
- Antenatal management focused on monitoring and intervention for potential complications.
- Successful delivery with specific maternal and fetal outcomes documented.
Conclusions:
- Large placental chorioangiomas necessitate careful antenatal surveillance and management.
- Effective management can mitigate risks and improve perinatal outcomes.
- This case underscores the importance of timely diagnosis and intervention for placental tumors.
Related Concept Videos
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Disorders of the Female Reproductive System
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Cancer
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
