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Sterile osteitis and suppurative arthritis associated with pannus responding to colchicine
Mehmet Engin Tezcan1, Ozgür Ekinci, Murat Uçar
1Division of Rheumatology, Department of Internal Medicine, Gazi University Medical Faculty, Beşevler, 06500 Ankara, Turkey.
Abstract:
Sterile suppurative arthritis is characterized by neutrophilic infiltration of joints without any causative pathogen. Here, we present a 32-year-old man with refractory osteitis and erosive suppurative oligoarthritis with pannus. Treatments with multiple disease modifying antirheumatic drugs were all unsuccessful. However, he had clinical response to colchicine and the synovial hypertrophy and the pannus in the MRI of his left shoulder resolved. In this case, the effects of colchicine on neutrophils might have played a role in treating neutrophilic sterile suppurative arthritis, which, in adults, might be a distinct oligoarticular disease.
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