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Updated: May 8, 2026

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
[A case of massive perioperative bleeding in a patient on two-drug antiplatelet therapy undergoing abdominal surgery]
Yuriko Imao1, Mitsuru Ogawa, Takashi Abe
1Department of Anesthesiology, Niigata University Medical and Dental Hospital, Niigata 951-8520.
Abstract:
We report a patient on two-drug antiplatelet therapy who underwent total gastrectomy, and developed massive perioperative bleeding. The operation was performed seven months after the placement of a drug-eluting stent (DES) for unstable angina. In perioperative care of patients with placed DES, we need to remember the risks of stent thrombosis and hemorrhagic complications, and consider the withdrawal of the antiplatelet drugs.
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