Related Experiment Video
Updated: May 8, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
[Surgical ventricular restoration for functional mitral regurgitation]
Masaki Funamoto1, Kenji Minakata, Kazuhiro Yamazaki
1Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Surgical ventricular restoration (SVR) improved leaflet tethering and mitral regurgitation in severe left ventricular dilatation. However, long-term outcomes were poor for patients requiring SVR, despite initial benefits.
Area of Science:
- Cardiovascular Surgery
- Cardiac Mechanics
- Mitral Valve Disease
Context:
- Functional mitral regurgitation (FMR) due to severe leaflet tethering presents a complex surgical challenge.
- Comparing outcomes of mitral annuloplasty (MAP) alone versus MAP with surgical ventricular restoration (SVR) for FMR.
- Preoperative assessment revealed group S (MAP + SVR) had lower ejection fraction, larger left ventricle, and more severe mitral regurgitation than group M (MAP alone).
Purpose:
- To evaluate the effectiveness and limitations of surgical ventricular restoration (SVR) in patients with functional mitral regurgitation (FMR) caused by severe leaflet tethering.
- To compare the short-term and long-term outcomes of mitral annuloplasty (MAP) alone versus MAP combined with SVR for FMR.
Summary:
- Surgical ventricular restoration (SVR) combined with mitral annuloplasty (MAP) significantly reduced leaflet tethering and mitral regurgitation (MR) in patients with severe left ventricular (LV) dilatation.
- While LV dimensions decreased and MR grade improved in both groups, SVR did not significantly improve ejection fraction.
- Hospital mortality was higher in the SVR group (18%) compared to the MAP-alone group (0%), and late deaths were also more frequent in the SVR group.
Impact:
- SVR effectively addresses leaflet tethering and MR in severe LV dilatation, offering a potential solution for complex FMR cases.
- The study highlights significant limitations in long-term outcomes for patients undergoing SVR, suggesting careful patient selection is crucial.
- Findings indicate that while SVR provides anatomical benefits, its impact on long-term survival in this patient cohort requires further investigation and may be suboptimal.
Related Concept Videos
Mitral Regurgitation III: Medical Management
Mitral Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Mitral Regurgitation IV: Nursing Management
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management

