Related Experiment Video
Updated: May 8, 2026
Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
Published on: July 7, 2016
[Preserving autologous heart operation for dilated cardiomyopathy]
Joji Hoshino1, Yasuhisa Fukada, Masanori Hirota
1Department of Cardiovascular Surgery, Hayama Heart Center, Kanagawa, Japan.
Insights
Non-transplant heart surgery for dilated cardiomyopathy (DCM) showed significant hospital and late cardiac death rates. Stable preoperative condition is crucial for better surgical outcomes in DCM patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Heart Failure Research
Context:
- Dilated cardiomyopathy (DCM) presents a significant challenge in cardiac surgery.
- Non-transplant surgical procedures offer an alternative for managing DCM.
- Mitral regurgitation and left ventricular dilation are key considerations in DCM surgical management.
Purpose:
- To evaluate the clinical outcomes of non-transplant surgical procedures for dilated cardiomyopathy (DCM).
- To identify prognostic factors influencing survival after surgical intervention for DCM.
- To assess the effectiveness of specific surgical techniques, including mitral valve surgery and surgical left ventricular reconstruction (SVR).
Summary:
- A total of 258 patients underwent non-transplant surgical procedures for DCM over 11 years.
- Surgical interventions included mitral valve repair/replacement, papillary muscle plication, chordal cutting, and SVR, with SVR type determined by echocardiography.
- Hospital mortality was 18.2% and late cardiac death was 27.5%, with 5-year and 10-year survival rates of 58% and 39%, respectively.
Impact:
- Preoperative condition, emergent operation, inotropic support, and intra-aortic balloon pumping (IABP) significantly impacted prognosis.
- Left ventricular size was not found to be a significant prognostic factor.
- The study emphasizes the importance of performing surgical treatment for DCM patients under stable preoperative conditions to improve outcomes.
Objective:
We report non transplant surgical procedure (preserving autologous heart operation) for the patients with dilated cardiomyopathy( DCM), clinical outcomes, and the factor of predict prognosis.
Patient And Method:
Since May 2000, 258 patients received surgical procedure for 11 years.
Surgical Procedures:
We performed mitral surgery (plasty or replacement) for the patients with more than mild mitral regurgitation (MR). We performed papirally muscule plication since 2005, and we performed 2nd chordal cutting since 2008, for the patients with MR due to mitral tethering. The surgical left ventricular reconstruction( SVR) was performed for the patients with dilated left ventricular. We use spackle tracking echocardiography to decide the type of SVR since 2008.
Result:
Hospital death was 18.2%, and late cardiac death was 27.5%.Almost the cause of death was congestive heart failure and ventricular arrhythmia. Five years survival was 58%, 10 years survival was 39%. Preoperative condition, emergent operation, inotropic support, intra aortic balloon pumping(IABP),affect the prognosis. But left ventricular size did not affect it.
Conclusion:
Surgical treatment for the patient with DCM should be performed with stable preoperative condition.
Related Concept Videos
01:29Cardiomyopathy V: Interprofessional Care
01:30Cardiomyopathy II: Dilated Cardiomyopathy
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
01:28Cardiomyopathy VII: Pre and Post Operative Nursing Management