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Updated: May 8, 2026

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
Published on: February 2, 2022
[Renal allograft rupture: case report and bibliographic review]
Juan Francisco Galiano Baena1, Enrique Herrero Polo, Juan Pablo Caballero Romeu
1Urology Department. Hospital General Universitario de Alicante. Alicante. Spain.
Objective:
To improve the knowledge about complications of renal transplantation and, in particular, graft rupture.
Methods:
Case report and literature review.
Outcome:
We present the case of a 37 year-old patient receiving a second renal transplant. In the third postoperative day, he suffered an abrupt change from the correct evolution, with intense pain in the left iliac fossa (the side of the implant) and hemodynamic instability. Imaging tests suggested retroperitoneal collection and adjacent to the implant. In this situation we decided reoperation, we found a ruptured renal unit and transplant nephrectomy was carried out. The pathologic study confirmed that the cause of this rupture was acute rejection of the implant.
Conclusion:
The rupture of the graft is one of the most serious complications in renal transplantation. Rapid diagnosis and surgical treatment are required. Conservative management is the treatment of choice for possible preservation of the renal unit, but there are some situations in which it is dangerous and removal of the graft must be carried out.
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Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury III: Clinical Manifestations

