Body composition from birth to 6 mo of age in Ethiopian infants: reference data obtained by air-displacement

Gregers S Andersen1, Tsinuel Girma, Jonathan C K Wells

  • 1Steno Diabetes Center, Gentofte, Denmark.

Insights

This study provides crucial reference data for infant body composition, including fat mass (FM) and fat-free mass (FFM), in an urban African population. These findings are essential for understanding infant growth and future health outcomes.

Area of Science:

  • Pediatric Nutrition
  • Human Growth and Development
  • Body Composition Analysis

Background:

  • Infant body composition data is vital for understanding long-term disease risk.
  • Limited body composition data exists for infants in low-income settings.
  • New assessment techniques are available but underutilized in infant studies.

Purpose of the Study:

  • To establish reference data for fat mass (FM) and fat-free mass (FFM) in infants.
  • To cover the period from birth to 6 months of age.
  • To focus on an urban African population.

Main Methods:

  • Prospective cohort study in Jimma, Ethiopia.
  • Air-displacement plethysmography (ADP) used for FM and FFM measurements.
  • Lambda-mu-sigma method applied for constructing reference charts and tables.

Main Results:

  • 2026 body composition measurements from 378 infants were analyzed.
  • Fat mass and fat mass index (FMI) showed logarithmic growth patterns.
  • Fat-free mass (FFM) exhibited near-linear growth with a slight deceleration around 3 months.

Conclusions:

  • Presents the first z scores and centile reference charts for FM and FFM in an urban Ethiopian infant population.
  • Provides essential reference data for African infants, aiding clinical care and research.
  • Highlights the importance of context-specific body composition data.
Abstract

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