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Related Concept Videos

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Related Experiment Video

Updated: May 8, 2026

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

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Published on: May 25, 2017

Alerting physicians during electronic order entry effectively reduces unnecessary repeat PCR testing for Clostridium

Robert F Luo1, Suzanne Spradley, Niaz Banaei

  • 1Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

Journal of Clinical Microbiology
|August 30, 2013
PubMed
Summary

Hospital information systems (HIS) alerts significantly reduced repeat Clostridium difficile PCR tests by 91%. This intervention improved the quality and utilization of diagnostic results for this common infection.

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Published on: June 15, 2018

Area of Science:

  • Clinical Informatics
  • Infectious Disease Diagnostics
  • Healthcare Quality Improvement

Background:

  • Repeat testing for Clostridium difficile infection (CDI) can lead to unnecessary costs and resource utilization.
  • Physician ordering practices for CDI diagnostic tests require optimization to improve efficiency.

Purpose of the Study:

  • To evaluate the impact of hospital information systems (HIS) alerts on reducing repeat Clostridium difficile PCR testing.
  • To assess the effectiveness of a targeted, patient-specific intervention in improving CDI test utilization.

Main Methods:

  • Implementation of HIS alerts to restrict repeat Clostridium difficile PCR orders within a 7-day window.
  • Comparative analysis of repeat test rates before and after the intervention period.

Main Results:

  • A 91% reduction in repeat Clostridium difficile PCR tests was observed postintervention.
  • Repeat test rates decreased from 14.5% preintervention to 1.3% postintervention, representing a significant improvement in test utilization.

Conclusions:

  • HIS alerting systems are highly effective in reducing unnecessary repeat diagnostic tests.
  • Implementing HIS alerts is a valuable strategy for enhancing the quality and efficient utilization of Clostridium difficile results.