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Related Concept Videos

Curing Methods01:26

Curing Methods

Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...
Curing of Concrete01:20

Curing of Concrete

The hydration of cement takes place within the water-filled capillary pores. However, environmental elements can disrupt this process by evaporating water from the concrete surfaces. Sealed concrete with a water-cement ratio below 0.5 experiences self-desiccation, leading to water loss. The water loss in concrete is mitigated by curing. This technique involves keeping the concrete saturated to maintain the necessary temperature and moisture conditions, to optimally fill the spaces in the cement...
Fatigue01:21

Fatigue

Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
Muscle Recovery and Fatigue01:24

Muscle Recovery and Fatigue

Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective response...
Accelerated Curing of Concrete01:25

Accelerated Curing of Concrete

Accelerating concrete curing is achieved by applying heat and additional moisture. This process accelerates the hydration of the cement, resulting in an earlier strength gain in the concrete. Steam curing is a method wherein the concrete products are either transported through a chamber on a conveyor belt or encased in plastic, allowing steam at atmospheric pressure to circulate freely around them. This process begins with a phase of moist curing that typically lasts between 3 to 5 hours, after...
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
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Curing consortium fatigue.

Magdalini Papadaki1, Gigi Hirsch

  • 1Massachusetts Institute of Technology (MIT) Center for Biomedical Innovation, Cambridge, MA 02139, USA.

Science Translational Medicine
|August 30, 2013
PubMed
Summary
This summary is machine-generated.

Consortium fatigue, a complex issue in biomedical innovation, offers insights into improving collaborative efforts. Understanding its pathology is key to fostering more effective partnerships.

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Area of Science:

  • Biomedical innovation
  • Collaborative research
  • Organizational psychology

Background:

  • Biomedical innovation relies heavily on interdisciplinary collaboration.
  • Effective collaboration is often hindered by complex interpersonal and organizational dynamics.
  • Consortium fatigue is an emerging challenge impacting the sustainability of research partnerships.

Purpose of the Study:

  • To define and characterize the pathology of consortium fatigue.
  • To identify diagnostic indicators of consortium fatigue within collaborative biomedical projects.
  • To provide actionable data for enhancing collaboration in biomedical innovation.

Main Methods:

  • Qualitative analysis of case studies involving biomedical consortia.
  • Diagnostic framework development based on observed patterns of collaboration breakdown.
  • Literature review on team dynamics and organizational fatigue in research settings.

Main Results:

  • Consortium fatigue presents with symptoms such as decreased communication, goal misalignment, and resource depletion.
  • Diagnostic data reveals that unclear roles and leadership challenges are primary contributors.
  • The study identified key indicators for early detection of fatigue within research teams.

Conclusions:

  • Addressing the complex pathology of consortium fatigue is crucial for successful biomedical innovation.
  • Implementing strategies based on diagnostic data can mitigate fatigue and improve collaborative outcomes.
  • Further research should focus on developing and testing interventions to prevent and manage consortium fatigue.