[Obstructive complications of endoscopic treatment of vesicoureteral reflux in children]
Related Experiment Video
Updated: May 8, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Insights
Endoscopic treatment for vesicoureteral reflux (VUR) is contraindicated in children with high-degree reflux and signs of ureteral obstruction. This prevents obstructive hydroureteronephrosis (HUN) and preserves upper urinary tract function.
Area of Science:
- Pediatric Urology
- Surgical Innovation
- Reflux Management
Context:
- Vesicoureteral reflux (VUR) is common in children.
- Endoscopic treatment is a widely used VUR intervention.
- Obstructive hydroureteronephrosis (HUN) is a potential complication.
Purpose:
- To identify patient selection criteria for VUR endoscopic treatment.
- To determine contraindications for endoscopic VUR treatment.
- To prevent obstructive hydroureteronephrosis (HUN) post-VUR treatment.
Summary:
- Endoscopic VUR treatment was performed in over 4,000 children (4 months-17 years) from 1991-2011.
- Obstructive HUN occurred in 0.5% of cases, exclusively in those with IV-degree VUR and pre-existing ureteral obstruction.
- Radiological signs included flask-shaped juxtavesical ureter extension.
Impact:
- Identifies specific patient groups at high risk for obstructive HUN.
- Contraindicates endoscopic VUR treatment in children with high-degree reflux and ureteral obstruction signs.
- Highlights the importance of pre-treatment evaluation to avoid iatrogenic complications.
Abstract:
The study was aimed to the selection of patients, in which endoscopic treatment of vesicoureteral reflux (VUR) is contraindicated due to the high risk of the formation of obstructive hydroureteronephrosis (HUN). From June 1991 to December 2011, endoscopic treatment of I-V degree VUR was performed in more than 4,000 children aged 4 months to 17 years. In period of wide use of endoscopic technique, obstructive HUN occurred in average in 1 (0.5%) case of 200 VUR (5 cases in 5 children), only in IV degree reflux and in only in children with initial subcompensated obstruction of ureterovesical segment, which was manifested as flask-shaped extension of juxtavesical ureter on intravenous urograms. Ureterocystoneostomy allowed to resect the terminal ureter with encapsulated implants in 4 out of 5 children. The macroscopic and histological examination of biopsy specimens confirmed the correct position of the implant in all cases, which excluded the technical complications. Thus, persistent decompensation of urodynamics of upper urinary tract is the result of increased pressure profile of the terminal ureter, inevitable in the endoscopic treatment of UVR, in children with initial obstruction of ureterovesical segment. Therefore, endoscopic treatment is contraindicated for children with high-degree reflux and radiological signs of obstruction of the terminal ureter.
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