Related Experiment Video For Biopsia intraocular
Updated: May 8, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
[Combined choroidal biopsy and cytology for diagnosis of intraocular tumour]
A Sala-Puigdollers1, E Rodríguez-de la Rúa, M A Saornil
1Hospital Clínico Universitario de Valladolid, Universidad de Valladolid, Valladolid, España. annasalapuigdollers@hotmail.com
Clinical Case:
No intraocular biopsy technique is free of risk and all have the possibility of giving false negatives due to the difficulty in obtaining a sufficient sample. A modified chorioretinal biopsy was performed on a patient with suspected choroidal melanoma after negative biopsy with 25G vitrectomy. In addition to removing a solid fragment of tumor material using bimanual surgery, material from the lesion was obtained with the vitreotome to perform cytology, which confirmed the diagnosis of melanoma.
Discussion:
Cytology obtained through the vitreotome in association with removing a solid sample of the choroidal lesion may improve the efficiency of intraocular biopsy.
