Related Experiment Video
Updated: May 8, 2026

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Underutilization of cardiovascular medications: effect of a continuity-of-care program
Emily N Israel1, T Michael Farley, Karen B Farris
1University of Michigan Health System, Ann Arbor, MI, USA.
Insights
Enhanced pharmacist interventions did not improve the underutilization of cardiovascular medications. Communication efforts with patients and providers did not change medication use patterns during or after hospitalization.
Area of Science:
- Cardiovascular medicine
- Health services research
- Pharmaceutical care
Background:
- Underutilization of key cardiovascular medications remains a challenge in patient care.
- Hospital pharmacists play a crucial role in medication management and patient communication.
Purpose of the Study:
- To investigate the impact of enhanced communication by hospital pharmacists on the underutilization of cardiovascular medications.
- To assess if pharmacist interventions improve medication adherence and guideline adherence.
Main Methods:
- A randomized controlled trial involving 732 patients with cardiovascular conditions.
- Three groups: minimal intervention, enhanced intervention, and usual care.
- Pharmacy case managers (PCMs) reconciled medications, identified problems, and made recommendations.
Main Results:
- No significant differences in medication underutilization were observed among the three study groups.
- Enhanced pharmacist interventions did not alter the rate of cardiovascular medication underutilization.
- Underutilization rates remained constant across all groups despite pharmacist involvement.
Conclusions:
- Enhanced communication strategies by pharmacy case managers did not reduce the underutilization of key cardiovascular drugs.
- Hospital pharmacist interventions, as implemented, had no discernible effect on medication use during or after hospitalization.
Purpose:
The effect of hospital pharmacists' enhanced communication with patients and community providers on the underutilization of key cardiovascular medications was studied.
Methods:
Patients enrolled in the Iowa Continuity of Care study were eligible for inclusion in this study if they had a diagnosis of hypertension, hyperlipidemia, heart failure, coronary artery disease, or a combination of these diagnoses. Eligible patients also had to be admitted to the internal medicine, family medicine, cardiology, or orthopedics services and receive their usual medical care in the community and their prescriptions from a community pharmacy. Patients were randomized to receive minimal intervention, enhanced intervention, or usual care. For the minimal- and enhanced-intervention groups, pharmacy case managers (PCMs) performed comprehensive medication reconciliations and identified drug-related problems within 24 hours of admission. The PCMs made recommendations to the inpatient care team and to patients' community physicians. For patients in the enhanced-intervention group, the PCM developed a discharge care plan containing the patient's discharge medication list. PCMs made specific recommendations to optimize regimens that did not meet current guidelines or medications that were underutilized. Medication underutilization was assessed at admission, discharge, 30 days after discharge, and 90 days after discharge.
Results:
A total of 732 patients were enrolled in this study. There were no significant differences among the three study groups. Overall, the rate of underutilization remained constant among all three groups, despite enhanced pharmacist involvement in both intervention groups.
Conclusion:
Enhanced interventions by PCMs had no effect on the underutilization of key cardiovascular drugs during hospitalization or after hospital discharge.
Related Concept Videos
Heart Failure V: Medical Management
Cardiomyopathy V: Interprofessional Care
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Heart Failure VI: Adjunct Therapies
Acute Coronary Syndrome IV: Interprofessional Care