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Updated: May 8, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Bilateral adrenal hemorrhage revealing hyperhomocysteinemia]
M Luwawu Mbimba1, A Monier1, C Tchanou2
1Service de médecine A, hôpital Louis-Pasteur, hôpitaux de Chartres, 4, rue Claude-Bernard, 28630 Le Coudray, France.
Introduction:
Bilateral adrenal hemorrhage remains a rare disease. It has several etiologies, and clinical presentation is not specific.
Case Report:
We report a 45-year old man without known prothrombotic factor who presented with acute left sided abdominal pain left revealing a bilateral adrenal hemorrhage. The diagnostic work-up identified a significant hyperhomocysteinemia associated with a previously undiagnosed homozygous mutation of the 5,10 methylene-tetrahydrofolate reductase gene. The outcome was associated with the occurrence of an adrenal insufficiency.
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