In-fiber integrated chemiluminiscence online optical fiber sensor

Area of Science:

• Analytical Chemistry
• Optical Sensing
• Microfluidics

Background:

• Traditional chemical analysis methods often require complex sample preparation and bulky instrumentation.
• Developing miniaturized, integrated sensors is crucial for real-time monitoring and point-of-care applications.
• Optical sensing offers high sensitivity and selectivity for various analytes.

Purpose of the Study:

• To develop and demonstrate an in-fiber integrated chemiluminescence (CL) sensor.
• To analyze hydrogen peroxide (H2O2) concentration using a novel microfluidic optical fiber.
• To establish the feasibility of optical methods for online analyzing devices.

Main Methods:

• Fabrication of a hollow optical fiber sensor with a suspended inner core and microfluidic channels.
• Utilizing a chemiluminescence reaction involving H2O2, luminol, K3Fe(CN)6, and NaOH within the optical fiber.
• Coupling emitted photons from the CL reaction into the optical fiber core for detection.

Main Results:

• Achieved a linear sensing range of 0.1-4.0 mmol/L for H2O2 concentration.
• Demonstrated rapid emission intensity determination within 400 ms at a flow rate of 150 μL/min.
• Successfully integrated microfluidics and CL detection within a single optical fiber.

Conclusions:

• The developed in-fiber CL sensor provides a sensitive and rapid method for H2O2 analysis.
• This technology enables the development of integrated online analyzing devices based on optical methods.
• The sensor design offers a promising platform for miniaturized chemical sensing applications.