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Related Concept Videos

Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

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Related Experiment Video

Updated: May 8, 2026

Experimental Human Pneumococcal Carriage
07:47

Experimental Human Pneumococcal Carriage

Published on: February 15, 2013

[Symptomatic diseases in pneumology].

J Behr1, K Avsar

  • 1Medizinische Klinik und Poliklinik V, Klinikum der Ludwig-Maximilians-Universität, Marchioninistr. 15, 81377, München, Deutschland, Juergen.Behr@med.uni-muenchen.de.

Der Internist
|August 31, 2013
PubMed
Summary

This article reviews granulomatous lung diseases, focusing on eosinophilic vasculitis with polyangiitis and tuberculosis. It details diagnostic approaches and treatment strategies for these challenging respiratory conditions.

Area of Science:

  • Pulmonology
  • Rheumatology
  • Infectious Diseases

Context:

  • Granulomatous lung diseases present diagnostic and therapeutic challenges.
  • Eosinophilic vasculitis with polyangiitis involves bronchial asthma and eosinophilic granulomatous vasculitis.
  • Tuberculosis remains a concern, particularly in Germany, requiring updated diagnostic and treatment protocols.

Purpose:

  • To describe the clinical characteristics, diagnosis, and treatment of eosinophilic vasculitis with polyangiitis.
  • To outline the current status of tuberculosis in Germany, including diagnostic advancements and treatment guidelines.
  • To provide an overview of managing complex granulomatous lung diseases.

Summary:

  • Eosinophilic vasculitis with polyangiitis treatment varies based on manifestation extent, from steroids for pulmonary-only cases to combined immunosuppression for systemic involvement.

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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
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A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

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Related Experiment Videos

Last Updated: May 8, 2026

Experimental Human Pneumococcal Carriage
07:47

Experimental Human Pneumococcal Carriage

Published on: February 15, 2013

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
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A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

  • Tuberculosis diagnosis is enhanced by PCR and interferon gamma release assays (IGRA), replacing traditional methods.
  • Standard tuberculosis treatment involves a four-drug regimen, with specialized approaches for drug-resistant strains (MDR/XDR).
  • Impact:

    • Improved understanding of treatment stratification for eosinophilic vasculitis with polyangiitis.
    • Highlights the importance of modern diagnostics like IGRA for tuberculosis detection.
    • Emphasizes the need for expert management of drug-resistant tuberculosis cases.