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Related Experiment Video

Updated: May 8, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

Intraparenchymal cyst development after deep brain stimulator placement.

Adolfo Ramirez-Zamora1, David Levine, David B Sommer

  • 1Department of Neurology, Albany Medical College, Albany, N.Y., USA.

Stereotactic and Functional Neurosurgery
|August 31, 2013
PubMed
Summary

Deep brain stimulation (DBS) can cause rare cysts at electrode tips, even without infection. Removing the affected DBS lead resolves these cysts and associated neurological deficits.

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Area of Science:

  • Neurosurgery
  • Neurology
  • Biomedical Engineering

Background:

  • Deep brain stimulation (DBS) is a common treatment for movement disorders.
  • Potential complications include hardware issues and infections.
  • Cyst formation at the electrode tip is a rare but significant complication.

Observation:

  • Two patients developed neurological deficits months after DBS surgery.
  • Imaging revealed cyst formation at the tip of the DBS electrode in both cases.
  • Cysts were unilateral and not associated with infection.

Findings:

  • Ventral intermediate nucleus lead for essential tremor and subthalamic nucleus leads for Parkinson's disease were implicated.
  • Removal of the affected DBS lead led to rapid symptom regression.

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Related Experiment Videos

Last Updated: May 8, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

  • Bacteriological cultures of removed electrodes were negative.

    • Implications:

    • This case series highlights a rare complication of DBS: electrode tip cyst formation.
    • Lead explantation is an effective treatment for resolving these cysts.
    • Understanding rare complications is crucial for optimizing DBS therapy and patient outcomes.