[Circulating blood plasma proteins during the infusion therapy of blood loss]

Experiments were conducted on 60 dogs to study the total protein level in circulation after acute and prolonged blood loss and infusion of salt and colloid solutions. It was found that the amount of circulating blood in the restorative period depends mainly on the individual initial values and to a lesser degree on the protein loss. A low protein level persists in infusion therapy. Infusion of colloid solutions inhibits mobilization of plasma protein reserve into the vascular channel as compared to that in infusion of salt solutions. The authors revealed two types of reactive changes in circulating protein in the restorative period after blood loss and infusion therapy.