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Published on: March 11, 2014
Respiratory papillomas: presentation before six months
B E Chipps1, F L McClurg, E M Freidman
1Department of Pediatrics and Surgery, Sutter Community Hospitals, Sacramento, California.
Insights
Respiratory papillomatosis (RP) in newborns has a poor prognosis, with a 100% mortality rate in this study. Current treatments were ineffective, highlighting the need for alternative management strategies for infant airway papillomas.
Area of Science:
- Pediatric Otolaryngology
- Neonatal Medicine
- Respiratory Diseases
Background:
- Respiratory papillomatosis (RP) is a rare condition affecting the airway.
- Early-onset RP in newborns presents unique challenges and a potentially worse prognosis compared to older children.
Abstract:
The prognosis of respiratory papillomatosis (RP) in newborns appears to be less favorable than in infants and older children. In this series of four patients who developed symptoms of the disease within the first 6 months of life, the mortality was 100%. In these premature and term newborn infants, endoscopic laser surgery and medical and immunologic therapy were unable to control the growth of RP. Meticulous local removal of the airway lesions is the most reliable form of management.
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