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Related Experiment Video

Updated: May 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Multiple clear-cell acanthomas.

Marcela Martínez Escanamé¹, Edith Arzberger, Rainer Hofmann-Wellenhof

¹Department of Dermatology, Medical University of Graz, Graz, Austria.

The Australasian Journal of Dermatology

|September 3, 2013

Summary

This summary is machine-generated.

Multiple clear-cell acanthomas (CCA) rarely present abruptly, posing diagnostic challenges. This case highlights the utility of dermoscopy and confocal microscopy for accurate diagnosis of this unusual presentation.

Keywords:

clear-cell acanthoma dermoscopy reflectance confocal microscopy

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Area of Science:

Dermatology
Oncology

Background:

Clear-cell acanthoma (CCA) is typically a solitary lesion on lower extremities.
Multiple CCA presentations are rare and can complicate diagnosis.

Observation:

A 52-year-old male presented with multiple clear-cell acanthomas.
The unusual clinical presentation prompted further investigation beyond standard methods.

Findings:

Dermoscopy is valuable for diagnosing clear-cell acanthoma.
Confocal microscopy enhanced diagnostic accuracy for this atypical case.

Implications:

This case underscores the importance of considering unusual presentations of CCA.
Advanced imaging techniques like confocal microscopy can aid in diagnosing rare dermatological conditions.