Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Skin: Sweat Glands01:20

Accessory Structures of the Skin: Sweat Glands

Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice.

Cellular and molecular life sciences : CMLS·2026
Same author

Retro- and prospective histologic and immunohistochemical analysis of safety margins following complete excision of less than 1 mm melanomas.

Melanoma research·2025
Same author

Validating instructional design and predicting student performance in histology education: Using machine learning via virtual microscopy.

Anatomical sciences education·2023
Same author

[When a metastasis hides another].

Revue medicale de Liege·2023
Same author

[Ulcerative Zoon's balanitis].

Revue medicale de Liege·2023
Same author

Effects of Minocycline Hydrochloride as an Adjuvant Therapy for a Guided Bone Augmentation Procedure in The Rat Calvarium.

Dentistry journal·2023

Related Experiment Video

Updated: May 8, 2026

Immunofluorescent Staining for Visualization of Heterochromatin Associated Proteins in Drosophila Salivary Glands
10:13

Immunofluorescent Staining for Visualization of Heterochromatin Associated Proteins in Drosophila Salivary Glands

Published on: August 21, 2021

Immunohistochemical sweat gland profiles.

Fanchon Noël1, Gérald E Piérard, Philippe Delvenne

  • 1Department of Dermatopathology, Liège University Hospital, Liège, Belgium.

Journal of Cosmetic Dermatology
|September 3, 2013
PubMed
Summary
This summary is machine-generated.

Immunohistochemistry using S100-B protein, CEA, and CD63 antibodies helps distinguish human sweat gland types. These markers reveal differences in secretory portions, aiding in identifying apoeccrine glands or specific eccrine gland functions.

Keywords:
CD138CD63CD68Ulex europaeus agglutinin-1sweat gland

More Related Videos

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

Three-dimensional Imaging and Analysis of Mitochondria within Human Intraepidermal Nerve Fibers
10:31

Three-dimensional Imaging and Analysis of Mitochondria within Human Intraepidermal Nerve Fibers

Published on: September 29, 2017

Related Experiment Videos

Last Updated: May 8, 2026

Immunofluorescent Staining for Visualization of Heterochromatin Associated Proteins in Drosophila Salivary Glands
10:13

Immunofluorescent Staining for Visualization of Heterochromatin Associated Proteins in Drosophila Salivary Glands

Published on: August 21, 2021

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

Three-dimensional Imaging and Analysis of Mitochondria within Human Intraepidermal Nerve Fibers
10:31

Three-dimensional Imaging and Analysis of Mitochondria within Human Intraepidermal Nerve Fibers

Published on: September 29, 2017

Area of Science:

  • Dermatology
  • Histology
  • Immunohistochemistry

Background:

  • Human sweat glands exhibit structural and functional heterogeneity.
  • Eccrine, apocrine, and apoeccrine glands are distinct types of sweat glands.

Purpose of the Study:

  • To identify immunohistochemical markers capable of distinguishing between human sweat gland types.
  • To investigate antigen expression in the secretory and excretory portions of sweat glands.

Main Methods:

  • Utilized two antibody panels targeting known and novel antigens.
  • Antibodies included markers for cytokeratins (CAM 5.2), S100-B protein, epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA), Ulex europaeus agglutinin-1 (UEA-1), syndecan-1 (CD138), CD63, and CD68.
  • Examined immunoreactivity in secretory and excretory segments of sweat glands.

Main Results:

  • Immunohistochemical markers confirmed similarities in the excretory ducts of all three sweat gland types.
  • Significant differences in immunoreactivity were observed in the coiled secretory portions, enabling distinction between gland types.
  • Novel antigen expressions were explored using the second antibody panel.

Conclusions:

  • S100-B protein, CEA, and CD63 antibodies provide valuable clues for distinguishing sweat gland types and their functional states.
  • These markers may aid in identifying apoeccrine sweat glands or specific functional activities within eccrine sweat glands.