Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modified-Release Drug Delivery Systems: Site-Targeted01:24

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishing mammography diagnostic reference levels in Mexico: A step towards improving patient radiation protection.

Radiography (London, England : 1995)·2025
Same author

An evaluation of the current status of quality assurance program in MRI: A multicenter study.

Radiography (London, England : 1995)·2025
Same author

Omentin-1 and its relationship with inflammatory factors in maternal plasma and visceral adipose tissue of women with gestational diabetes mellitus.

Journal of endocrinological investigation·2021
Same author

Synthesis and Biochemical Evaluation of Samarium-153 Oxide Nanoparticles Functionalized with iPSMA-Bombesin Heterodimeric Peptide.

Journal of biomedical nanotechnology·2020
Same author

Synthesis, chemical and biochemical characterization of Lu<sub>2</sub>O<sub>3</sub>-iPSMA nanoparticles activated by neutron irradiation.

Materials science & engineering. C, Materials for biological applications·2020
Same author

Evaluation of the effect of 1,3-bis-(4-phenyl-[1,2,3] triazole-1-il)2-propanol in comparison with metronidazole in an in vitro culture of <i>Blastocystis</i> in samples of patients with irritable bowel syndrome.

Journal of parasitic diseases : official organ of the Indian Society for Parasitology·2019
Same journal

Computational Study of ADME-TOx from Selected Phytocompounds of Solanum tuberosum and Cucumis sativus.

Current medicinal chemistry·2026
Same journal

QSAR-Based Strategies for Selective-HDAC6 Inhibitor Development: A Detailed Review.

Current medicinal chemistry·2026
Same journal

Breaking New Ground in Oncology: FDA Acceptance of Vepdegestrant NDA Marks a Milestone for PROTAC Therapies in Breast Cancer.

Current medicinal chemistry·2026
Same journal

Knockdown of circFGFR2 inhibits prostate cancer cell metastasis and proliferation by targeting miR-221-5p/ SMUG1 pathway.....

Current medicinal chemistry·2026
Same journal

LncRNA signature associated with amino acid metabolism: A novel prognostic tool for Clear Cell Renal Cell Carcinoma.

Current medicinal chemistry·2026
Same journal

HRI Kinase Modulation by BTdCPU as a Therapeutic Strategy for Bortezomib Resistance in Prostate Cancer.

Current medicinal chemistry·2026
See all related articles

Related Experiment Video

Updated: May 8, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

Multifunctional radiolabeled nanoparticles for targeted therapy.

G Ferro-Flores1, B E Ocampo-García, C L Santos-Cuevas

  • 1Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Carretera México-Toluca S/N. La Marquesa, Ocoyoacac, Estado de México, C.P. 52750, México. guillermina.ferro@inin.gob.mx.

Current Medicinal Chemistry
|September 3, 2013
PubMed
Summary
This summary is machine-generated.

Radiolabeled nanoparticles offer multifunctional capabilities for targeted cancer therapy. These agents combine diagnostic imaging, radiotherapy, and thermal-ablation for advanced cancer treatment strategies.

More Related Videos

Fabricating and Labeling Microbubbles with Fluorescent and Radioactive Tracers
10:40

Fabricating and Labeling Microbubbles with Fluorescent and Radioactive Tracers

Published on: January 24, 2025

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
09:02

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Published on: September 27, 2024

Related Experiment Videos

Last Updated: May 8, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

Fabricating and Labeling Microbubbles with Fluorescent and Radioactive Tracers
10:40

Fabricating and Labeling Microbubbles with Fluorescent and Radioactive Tracers

Published on: January 24, 2025

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
09:02

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Published on: September 27, 2024

Area of Science:

  • Nanomedicine
  • Radiochemistry
  • Oncology

Background:

  • Nanoparticles possess tunable optical (near-infrared fluorescence) or magnetic properties.
  • These properties enable applications in thermal therapy and molecular imaging.
  • Radiolabeled nanoparticles serve as versatile tools for cancer diagnosis and therapy.

Purpose of the Study:

  • To review the application of radiolabeled nanoparticles in developing multifunctional nanosystems.
  • To highlight their potential in targeted cancer therapy.

Main Methods:

  • Review of existing literature on radiolabeled nanoparticles.
  • Analysis of their properties and applications in oncology.

Main Results:

  • Radiolabeled nanoparticles act as multi-modal imaging agents.
  • They can function as simultaneous radiotherapy and thermal-ablation systems.
  • Multivalency of nanoparticles enhances their therapeutic efficacy.

Conclusions:

  • Radiolabeled nanoparticles are promising for multifunctional targeted cancer therapy.
  • Their combined diagnostic and therapeutic capabilities offer advanced treatment options.
  • Further development of these nanosystems is crucial for clinical translation.