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Published on: September 22, 2020
Percutaneous angioplasty of long tibial occlusions in critical limb ischemia
Nirvana Sadaghianloo1, Elixène Jean-Baptiste, Serge Declemy
1Department of Vascular Surgery, University Hospital of Nice, Nice, France.
Insights
Percutaneous angioplasty for long tibial occlusions shows a 65% midterm success rate in improving wound healing for critical limb ischemia patients. Maximal revascularization approaches enhance outcomes, despite technical challenges.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Therapy
Background:
- Critical limb ischemia (CLI) poses a significant challenge, particularly with long tibial occlusions.
- Percutaneous angioplasty is a potential treatment modality for limb salvage in these patients.
Purpose of the Study:
- To evaluate the midterm clinical outcomes of percutaneous angioplasty in patients with CLI and long tibial occlusions.
- To assess factors influencing clinical success, patency, and revascularization rates.
Main Methods:
- A prospective, single-center cohort study included 34 patients with 49 long tibial occlusions (>8 cm).
- Clinical success was defined as wound healing and survival without major amputation.
- Key outcomes examined included patency and freedom from target vessel revascularization (TVR).
Main Results:
- The 1-year clinical success rate was 65%, significantly higher with technical success (76%) and multiple patent tibial arteries (90%).
- Primary and secondary patency rates at 1 year were 13% and 32% respectively (24% and 58% excluding technical failures).
- The 1-year freedom-from-TVR rate was 34%.
Conclusions:
- Percutaneous angioplasty for long tibial occlusions can improve wound healing in CLI patients.
- Maximal revascularization strategies are crucial for enhancing outcomes.
- High technical failure rates necessitate repeat procedures but do not negate the benefits of angioplasty.
Background:
The aim of this study was to assess the midterm results of percutaneous angioplasty in patients with critical limb ischemia (CLI) and long tibial occlusions.
Methods:
Between January and September 2011, 34 consecutive patients with patent femoropopliteal artery and 49 segmental tibial occlusions >8 cm were included in our prospective, single-center cohort study. Clinical success (defined as wound healing and survival without major amputation), patency, and freedom from target vessel revascularization (TVR) were examined.
Results:
The median age of the patients was 75 (53-89) years, 74% were diabetic, and 89% of the limbs studied were Rutherford 5 and 6. Median follow-up was 12.5 (1-15) months. The 1-year clinical success rate was 65%, higher among patients with technical success (76% vs. 25%, P = 0.01) and patients with 2 or 3 patent tibial arteries after the procedure (90% vs. 41% in patients with only 1 patent artery, P = 0.003). At 1 year, primary and secondary patency rates were 13% and 32%, respectively (24% and 58% without technical failures). The 1-year freedom-from-TVR rate was 34%.
Conclusions:
Despite high technical failure rates and the need for repeat procedures, percutaneous angioplasty of long tibial occlusions enhances wound healing, especially when integrated into a maximal revascularization approach.
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