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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Pregnancy, somatic complaints and depression: a French population-based study
Gisèle Apter1, Emmanuel Devouche, Valérie Garez
1Erasme Hospital, Psychiatry and Psychopathology Research Institute, France.
Pregnant women reporting numerous somatic complaints face a significantly higher risk of antenatal depression. This finding highlights the importance of screening for physical symptoms to identify at-risk individuals for early intervention.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Mental Health
- Psychiatry
Background:
- Antenatal depression poses significant risks to both mothers and newborns.
- Current screening for depression is not routinely integrated into standard obstetric care.
- Somatic complaints are common during pregnancy and may indicate underlying mental health issues.
Purpose of the Study:
- To investigate the hypothesis that a high number of somatic complaints correlates with an increased risk of depression during pregnancy.
- To assess the utility of somatic complaints as a potential screening indicator for antenatal depression.
Main Methods:
- A cross-sectional study involving 1000 pregnant women during routine OB/GYN visits.
- Participants completed a questionnaire including the Edinburgh Postnatal Depression Scale (EPDS) and a checklist of 18 somatic complaints.
- Logistic regression analysis was used to evaluate the association between somatic complaints and depression risk.
Main Results:
- The median number of somatic complaints reported was 5.
- Antenatal depression (EPDS score > 10.5) was identified in 18.3% of women during the 2nd and 3rd trimesters.
- An increase in somatic complaints from 3 to 7 multiplied the odds of being at-risk for antenatal depression by 2.91.
Conclusions:
- The study suggests a significant link between the number of somatic complaints and the risk of antenatal depression.
- Further research is warranted to explore the relationship between somatic symptoms and pregnancy depression.
- Women with numerous somatic complaints during pregnancy should be considered at high risk and referred for clinical assessment.
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