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Updated: Sep 29, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
[Contrast medium assisted nuclear magnetic resonance tomography. Signal intensity of gliomatous tumors]
1Abteilung für Neuroradiologie, Justus-Liebig-Universität, Giessen.
Abstract:
In 124 patients with different types of gliomas signal intensity was studied with and without contrast material using T1-weighted sequences. The diagnostic possibilities equal those of computed tomography scans. Except grade II and III astrocytomas, the extent of the observed disorders of the blood-brain-barrier corresponds to the malignancy of the tumour. A distinction between glioblastomas, anaplastic astrocytomas and mixed gliomas is not possible. The differences on examination with and without contrast medium in grade I and II astrocytomas and grade I oligodendro-gliomas can be important for differential diagnosis. In addition the T1-weighted sequences require less time for investigation than other sequences which demonstrate disorders of the blood-brain-barrier without contrast material.

