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Updated: May 8, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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6-Cyclohexylmethoxy-5-(cyano-NNO-azoxy)pyrimidine-4-amine: a new scaffold endowed with potent CDK2 inhibitory

Donatella Boschi1, Paolo Tosco, Naveen Chandra

  • 1Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, via Pietro Giuria 9, 10125 Torino, Italy.

European Journal of Medicinal Chemistry
|September 3, 2013
PubMed

Keywords:
5-Substituted pyrimidine-4-amineCDK inhibitorCDK2 selective inhibitorCyano-NNO-azoxyWater-mediated hydrogen bond

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