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[Impulsive-compulsive syndrome in Parkinson's disease]
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|September 3, 2013
Summary
Dopaminergic replacement therapy for Parkinson's disease can cause impulse control disorders in 23% of patients. These disorders significantly impact quality of life, necessitating treatment adjustments.
Area of Science:
- Neurology
- Psychiatry
Background:
- Dopaminergic replacement therapy (DRT) effectively manages Parkinson's disease (PD) motor symptoms.
- DRT is associated with the development of impulse control disorders (ICD) in a subset of patients.
Purpose of the Study:
- To determine the prevalence of ICD in PD patients undergoing DRT.
- To assess the impact of ICD on patients' quality of life and daily functioning.
- To present treatment strategies for ICD in PD.
Main Methods:
- Cross-sectional study involving 246 Parkinson's disease patients.
- Diagnosis of ICD based on established criteria.
- Assessment of quality of life and functional impact.
Main Results:
- 23% of PD patients (55 out of 246) were diagnosed with ICD.
- Dopamine dysregulation syndrome and punding were the most common ICDs (36.4% each).
- ICD significantly affected patients' quality of life, with scores ranging from 25% to 89%.
Conclusions:
- Impulse control disorders are a significant comorbidity in Parkinson's disease patients treated with DRT.
- ICD negatively impacts patient quality of life and daily activities.
- Treatment requires careful management of dopaminergic medication.
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