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Related Concept Videos

Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
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Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Dementia01:30

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Updated: May 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

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Published on: January 11, 2020

Reversible mild cognitive impairment--a case report.

Madhavan Seshadri1, Nadeem Mazi-Kotwal, Mark Aguis

  • 1Weller Wing Mental Health Unit, South Essex Partnership University NHS Foundation Trust, Bedford, UK, seshmadhavan@gmail.com.

Psychiatria Danubina
|September 3, 2013
PubMed
Summary
This summary is machine-generated.

Mild Cognitive Impairment (MCI) can be reversible, as demonstrated by a bipolar disorder patient who recovered cognitive function after Parkinson's disease treatment. This case highlights the importance of accurate diagnosis and intervention for MCI.

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Area of Science:

  • Neuroscience
  • Gerontology
  • Psychiatry

Background:

  • Memory clinics aim for early dementia diagnosis and management.
  • Mild Cognitive Impairment (MCI) is a precursor to dementia in many cases.
  • Current guidelines recommend regular monitoring for MCI patients.

Observation:

  • A patient with late-onset bipolar disorder was diagnosed with MCI.
  • The patient later developed Parkinson's disease, treated successfully with levodopa.
  • Neuropsychological tests showed significant cognitive improvement post-Parkinson's treatment.

Findings:

  • The patient recovered from MCI, suggesting potential reversibility.
  • Differential diagnosis and causative factors for MCI in this case were explored.
  • Effective treatment of underlying neurological conditions can improve MCI.

Implications:

  • This case challenges the view of MCI as always progressive.
  • It underscores the need for comprehensive assessment and treatment of comorbidities.
  • Further research into modifying MCI course with interventions is warranted.