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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: May 8, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

Donor risk prediction: how 'extended' is safe?

Gregory I Snell1, Glen P Westall, Takahiro Oto

  • 1aLung Transplant Service, Alfred Hospital and Monash University, Melbourne, Australia bDepartment of Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmacological Sciences, Okayama, Japan.

Current Opinion in Organ Transplantation
|September 3, 2013
PubMed
Summary

Expanding donor lung utilization through new strategies significantly increases organ use to over 50% without compromising patient outcomes. Extended criteria donor lungs are safe for transplantation.

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Study of Experimental Organ Donation Models for Lung Transplantation
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Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

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Last Updated: May 8, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
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Published on: August 17, 2022

Using Quantitative Real-time PCR to Determine Donor Cell Engraftment in a Competitive Murine Bone Marrow Transplantation Model
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Using Quantitative Real-time PCR to Determine Donor Cell Engraftment in a Competitive Murine Bone Marrow Transplantation Model

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Study of Experimental Organ Donation Models for Lung Transplantation
08:56

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Area of Science:

  • Pulmonology
  • Transplant Surgery
  • Organ Donation

Background:

  • Lung transplantation is limited by donor organ scarcity.
  • This scarcity leads to prolonged waiting times and increased mortality for patients.
  • Optimizing donor organ selection is crucial to improve transplant rates.

Purpose of the Study:

  • To review recent advancements in lung donor selection.
  • To identify strategies for increasing the utilization of donor lungs.
  • To assess the safety and efficacy of using extended criteria donor lungs.

Main Methods:

  • Review of current literature on lung donor selection and management.
  • Analysis of strategies aimed at expanding the donor pool.
  • Evaluation of outcomes associated with extended criteria donor lungs.

Main Results:

  • Donor lung utilization rates can increase from <15% to >50% with expanded donor pool strategies.
  • These strategies do not appear to introduce inordinate short-term or long-term complications.
  • Extended criteria donor lungs demonstrate safe outcomes under current management protocols.

Conclusions:

  • Current management strategies support the safe use of lungs from extended criteria donors.
  • Traditional factors defining extended donors do not negatively impact outcomes.
  • Increased donor lung utilization is achievable and beneficial for transplant candidates.