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Updated: May 8, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Transradial intervention via large-bore guide catheters: a study of coronary bifurcation disease treatment using the
Paul D Williams1, Jonas Eichhöfer, Mamas A Mamas
1St Vincent’s Hospital, Melbourne, VIC 3065, Australia. dr.pdwilliams@gmail.com
Insights
Transradial access enables complex coronary interventions like crush stenting, achieving high success rates and excellent outcomes. This approach reduces vascular complications, offering a safe alternative for patients with bifurcation disease.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Access
Background:
- Transradial access (TRA) for coronary intervention minimizes vascular complications and major adverse cardiovascular events.
- The radial artery's small caliber traditionally limits complex interventions.
- True bifurcation lesions often require complex strategies like two-stent techniques.
Purpose of the Study:
- To evaluate the feasibility and outcomes of crush stenting for true bifurcation disease using the transradial approach.
- To assess procedural success and medium-term clinical outcomes in patients undergoing complex PCI via TRA.
Main Methods:
- A prospective study involving 53 patients with true bifurcation disease indicated for a two-stent strategy.
- Crush stenting performed via the transradial approach.
- Procedural outcomes and 6- and 18-month clinical follow-up were meticulously recorded.
Main Results:
- Successful crush stenting was achieved in 93% of lesions (51/55).
- Successful final kissing inflation was accomplished in 96% of cases (51/53).
- No in-hospital or procedural complications were reported; 18-month follow-up showed a 9.8% rate of death, myocardial infarction, or target vessel revascularization.
Conclusions:
- Complex percutaneous coronary intervention (PCI), including crush stenting, can be successfully performed via the transradial approach in a high proportion of patients.
- The transradial approach for crush stenting demonstrated excellent procedural success and favorable medium-term clinical outcomes.
- High rates of final kissing inflation were achieved, contributing to the positive results.
Abstract:
Transradial access for coronary intervention significantly reduces vascular complications and may be associated with a reduced risk of major adverse cardiovascular events. However, the small caliber of the radial artery has been considered a limitation to performing complex coronary intervention. Fifty-three patients with true bifurcation disease, in whom a two-stent strategy was felt to be indicated, were scheduled to undergo crush stenting via the transradial approach. Procedural outcome was recorded and 6- and 18-month clinical follow-up was performed. Successful crush stenting via the radial artery was performed in 51/55 lesions (93%). Crush stenting was performed in 53 lesions overall and successful final kissing inflation was achieved in 51/53 (96%). There were no in-hospital or procedural complications. The overall rate of death, myocardial infarction, or target vessel revascularization was 9.8% at 18-month follow-up. Complex percutaneous coronary intervention requiring large-bore catheters can be performed successfully in a high proportion of patients via the transradial approach. Crush stenting, with a very high rate of final kissing inflation, was associated in this series with excellent procedural and medium-term outcomes.
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