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Updated: May 8, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Development of aortic coarctation following device closure of patent ductus arteriosus
Arpan R Doshi1, P Syamasundar Rao
1Department of Pediatrics, Division of Pediatrics Cardiology, University of Texas Health Science Center at Houston/Children's Memorial Hermann Hospital, Houston Texas, USA. dr.arpan@gmail.com
Insights
Transcatheter closure of a large patent ductus arteriosus can lead to aortic coarctation. Transcatheter management effectively relieves this obstruction once it develops.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Patent ductus arteriosus (PDA) is a common congenital heart defect.
- Transcatheter closure is a standard treatment for PDA.
Observation:
- A patient treated for a large PDA in infancy developed aortic coarctation during follow-up.
- The coarctation was initially treated with balloon angioplasty and stent implantation.
Findings:
- Transcatheter management, including angioplasty and stenting, successfully relieved the aortic obstruction.
- The case highlights a potential complication of PDA closure devices.
Implications:
- Avoiding large closure devices in infants may prevent aortic obstruction.
- Modifying current devices could reduce the risk of iatrogenic aortic coarctation.
- Transcatheter interventions are effective for managing acquired aortic coarctation.
Abstract:
A patient who had transcatheter closure of a large patent ductus arteriosus in early infancy developed aortic coarctation during follow-up. Initially, balloon angioplasty and subsequent stent implantation successfully relieved the aortic obstruction. Avoidance of use of large devices in small babies and modification of current devices so that they do not cause aortic obstruction may result in better outcomes. Once aortic obstruction develops, transcatheter management is useful in relieving the obstruction.
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